Cases of lepromatous leprosy are treated with a combination therapy involving the use of the following: The skin biopsy shows few bacilli and there is a positive skin test. Combination therapy is recommended for all types of leprosy to avoid the emergence of resistance. The course of this subtype is progressive and malignant. In case of tuberculoid leprosy the course is more benign with cellular immunity remaining intact. Leprosy is of two types namely lepromatous and tuberculoid.This patient is suffering from lepromatous leprosy on account of the symmetric nerve involvement, the abundant acid fast bacilli and the negative lepromin test. Adverse side effects include gastrointestinal distress, asthenia, and headache but not anemia, leukopenia, or thrombocytopenia. The drug is remarkably nontoxic and adverse effects are mild. Tenofovir is a nucleoside reverse transcriptase inhibitor and anti-HIV drug that competitively inhibits reverse transcriptase and causes chain termination after incorporation into DNA. It is used in the treatment of hepatitis B virus infection. It is not associated with bone marrow suppression. Lamivudine is a nucleoside inhibitor and is an active inhibitor of HIV reverse transcriptase. Acyclovir has no significant toxicity on the bone marrow. Nelfinavir is a protease inhibitor that is characterized by a short half-life and has a number of drug interactions but its primary adverse effect is diarrhea and it has the most favorable safety profile in pregnancy. Acyclovir is commonly used for the treatment of mucocutaneous and genital herpes lesions and for prophylaxis in AIDS. Additional side effects include thrombocytopenia, gastrointestinal distress, headache, myalgia, acute cholestatic hepatitis, agitation, and insomnia. Zidovudine (ZDV,) formerly called azidothymidine, is active orally and is distributed to most tissues. The primary toxic side effect of ZDV is bone marrow suppression leading to anemia and neutropenia, which may require transfusions.

Cyber terminators critical ops hack